Chemical Glycomics – From Carbohydrate Arrays to a Malaria Vaccine
نویسنده
چکیده
Chemical glycomics uses synthetic chemistry to procure defined carbohydrate molecules to study the glycans involved in many functions in the living cell. Based on an automated synthesis platform, a host of synthetic tools including carbohydrate microarrays has been developed. These tools have been employed to dissect carbohydrate-copolymer interactions. Basic research in the glycomics arena is beginning to impact on drug discovery, especially the development of carbohydrate-based vaccines. The development of vaccine candidates to protect from malaria and leishmaniasis infections is discussed.
منابع مشابه
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